This is an ideal dietary supplement for people with knee pain and is a remarkable example of nutritional science – being a delicately balanced formula to improve bone and joint health and combating debilitating bone-joint diseases. This is a perfect combination which contains Calcitriol, Calcium Carbonate, and Zinc as active ingredients. The components in combination are helping body in Low blood calcium levels in people who do not get enough calcium from their diets Conditions caused by low calcium levels such as bone loss (osteoporosis), weak bones (osteomalacia/rickets), decreased activity of the parathyroid gland (hypoparathyroidism), and a certain muscle disease (latent tetany).
Pregabalin 75 mg
Methylcobalamin 750 mcg
Soft gel
Supplement
Pregabalin is an anticonvulsant drug used for neuropathic pain and as an adjunct therapy for partial seizures with or without secondary generalization in adults. Methylcobalamin is the neurologically active form of vitamin B12. Vitamin B12 comes in several kinds including hydroxy, cyano, and adenosyl, but only the methyl and adenosyl forms are active within the body. Methylcobalamin donates methyl groups to the myelin sheath that insulates nerve fibres and regenerates damaged neurons. In a B12 deficiency, toxic fatty acids destroy the myelin sheath but high enough doses of B12 can repair it. It has been demonstrated by recent studies that combination of Pregabalin and Methylcobalamin shows significantly better symptoms relief with the modest improvement of nervous system, chronic pain, perioperative pain, migraine and enhances immune system function.
Pregabalin is a structural analog of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA). It has been reported that its action presents the function of modulating the release of many excitatory neurotransmitters such as glutamate, norepinephrine, subtance-P and calcitonin gene related peptide. This modulation can cause an inhibitory modulation of overexcited neurons allowing them to get back to a normal state, including the decrease on the hyper excitability caused by tissue damage. The neurotransmitter modulation allows pregabalin to present antiallodynic, anxiolytic and anticonvulsant activity.
Pregabalin is contraindicated in patients with known hypersensitivity to pregabalin or any of its components. Vitamin B12 supplementation is generally regarded as safe during pregnancy and lactation.
Dizziness, drowsiness, headache, anorexia (loss of appetite), nausea or vomiting, diarrhea, headache, hot sensation (burning pain), vision problems, and diaphoresis (sweating)